Information on Alternatives
Guidance
Federal regulations stipulate that an investigator must consider alternatives to the use of animals and any procedures that may cause pain and distress (9CFR §2.31,c,8,d,ii; Policies #11 and 12 of the USDA APHIS Animal Care Policy Manual). To comply with these regulations, the Animal Care and Use Committee requires that you provide your search criteria (databases used, date the search was conducted, years covered by the search, keywords) as well as a short summary of your search results.
The Animal Care and Use Committee (ACUC) require this information be presented in the form of a literature search. For your convenience, the ACUC developed a guideline, Literature Searches for Alternatives, to help you conduct a literature search for alternatives. Additional information and helpful tips can be found in the “References” section of the ACUC guideline and on the following websites/documents:
- USDA Animal Welfare Information Center (AWIC) Alternatives Literature Searching
- Animal Welfare Institute’s Refinement database
- Alternatives to Laboratory Animals (ATLA) Journal
- Altweb
- ILAR: Institute for Laboratory Animal Research Author: National Academies; Division on Earth & Life Studies
- The National Centre for the 3Rs (NC3Rs)
- North American 3Rs Collaborative (NA3RsC)
- Norway’s National Consensus Platform for the Advancement of the 3Rs (Norecopa)